The report server cannot open a connection to the report server database. A connection to the database is required for all requests and processing. (rsReportServerDatabaseUnavailable)
It took me a while to realize/remember that the MT application I was running locally uses the credentials in web.config for the report viewer:
<add key="ReportServerAccessAccountUsername" value="ReportServiceAccount"/>
<add key="ReportServerAccessAccountPassword" value="Tr@p3z3"/>
<add key="ReportServerAccessAccountDomain" value="AZ-Dev5"/>